Description

2-Amino-N,n-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3-Pyridinecarboxamide is a high-value, multi-functional boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a monomer or functionalizing agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed as a tool compound or linker in the development of biochemical probes and affinity reagents.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.
• Ligand Synthesis: Used to construct sophisticated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Amino-N,n-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3-Pyridinecarboxamide
CAS No.	1092580-90-9
Molecular Formula	C14H22BN3O3
Molecular Weight	291.16 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-amino-N,N-dimethylnicotinamide; 2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethyl-3-pyridinecarboxamide; 3-Pyridinecarboxamide, 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethyl-; Pinacol 2-Amino-5-(N,N-dimethylcarbamoyl)pyridine-3-boronate; 2-Amino-N,N-dimethyl-5-(pinacolatoboryl)nicotinamide; 5-(Pinacolatoboryl)-2-amino-N,N-dimethylnicotinamide; Boronic acid, B-[2-amino-5-[(dimethylamino)carbonyl]-3-pyridinyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our production of 2-Amino-N,n-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3-Pyridinecarboxamide adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for advanced applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.