Description

5-Bromo-4-Chloro-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which serves as a critical scaffold for constructing complex molecules with tailored electronic and steric properties. It is primarily needed by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, particularly in kinase inhibitor and other small-molecule drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other biologically active small molecules.
• Agrochemical Research: Used as a building block for developing new crop protection agents and herbicides.
• Material Science: Serves as a monomer or functional unit in the creation of organic electronic materials and specialty polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Organic Synthesis: A versatile halogenated substrate for cross-coupling reactions (e.g., Suzuki, Sonogashira) and further functionalization.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.

Basic Information

Product Name	5-Bromo-4-Chloro-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1092579-75-3
Molecular Formula	C7H3BrClIN2
Molecular Weight	372.37 g/mol
Synonyms	5-Bromo-4-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-4-chloro-3-iodo-; 5-Br-4-Cl-3-I-1H-pyrrolo[2,3-b]pyridine; Multi-halogenated pyrrolopyridine; Halogenated heterocyclic building block
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.