Description

Morpholine, 4-[[2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl]- is a specialized organoboron building block designed for advanced pharmaceutical and agrochemical synthesis. This compound matters because it provides a versatile handle for Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern medicinal chemistry for creating complex carbon-carbon bonds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to accelerate the discovery and production of novel active ingredients. The CAS number for this compound is 1092564-33-4.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used to construct novel herbicide and fungicide candidates by introducing complex aromatic and heterocyclic systems.
• Material Science: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation strategies and the development of molecular tools.
• Catalyst Ligand Synthesis: Used to create novel, complex ligands for transition metal catalysts.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Morpholine, 4-[[2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl]-
CAS No.	1092564-33-4
Molecular Formula	C17H25BClNO3
Molecular Weight	337.65 g/mol
Synonyms	4-((2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)morpholine; 2-Chloro-4-(morpholinomethyl)phenylboronic acid pinacol ester; (2-Chloro-4-(morpholinomethyl)phenyl)boronic acid pinacol ester; 4-((2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl)morpholine; Morpholine, 4-[(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl]-; 1092564-33-4
EINECS	Contact for details

Quality Control

Every batch of our Morpholine, 4-[[2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl]- undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, critical for sensitive cross-coupling reactions. Our quality protocols are designed to meet the stringent requirements of GMP and ISO 9001 standards for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.