Description

1-(1-Boc-4-Piperidyl)-5-Methylpyrazole-4-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate belonging to the class of protected piperidine boronic acid esters. This compound is a critical building block in modern medicinal chemistry, enabling the efficient synthesis of complex molecules through versatile cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex heterocyclic compounds.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and probes for target identification and validation studies.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries for biological screening.

Basic Information

Product Name	1-(1-Boc-4-Piperidyl)-5-Methylpyrazole-4-Boronic Acid Pinacol Ester
CAS No.	1092563-67-1
Molecular Formula	C20H34BN3O4
Molecular Weight	391.32 g/mol
Synonyms	1-(1-Boc-4-Piperidyl)-5-Methyl-1H-pyrazole-4-boronic acid pinacol ester; 5-Methyl-1-(1-Boc-4-piperidyl)pyrazole-4-boronic acid pinacol ester; 1-(1-tert-Butoxycarbonyl-4-piperidinyl)-5-methyl-1H-pyrazole-4-boronic acid pinacol ester; 1-(1-Boc-piperidin-4-yl)-5-methyl-1H-pyrazole-4-boronic acid pinacol ester; 1-(1-Boc-4-piperidinyl)-5-methyl-1H-pyrazole-4-boronic acid pinacol ester; 1-(1-Boc-4-piperidyl)-5-methylpyrazole-4-boronate pinacol ester; 1-(1-Boc-4-piperidyl)-5-methyl-1H-pyrazole-4-boronic acid, pinacol ester; 1-(1-Boc-4-piperidyl)-5-methylpyrazole-4-Bpin
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles. We adhere to strict quality management protocols suitable for research and development applications, with the capability to supply material under GMP guidelines for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.