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n-(2-(Dimethylamino)Ethyl)-n-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinamide CAS NO 1092563-60-4
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CAS No.:1092563-60-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-(2-(Dimethylamino)Ethyl)-n-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinamide is a sophisticated boronic ester derivative, a key intermediate in modern synthetic chemistry. Its value lies in its dual functionality, combining a picolinamide core with a protected boronic acid group, making it a versatile building block for complex molecule assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients through cross-coupling reactions.
Application
- Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
- Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require complex boron-containing scaffolds.
- Material Science: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
- Chemical Biology: Employed as a probe or linker in bioconjugation and the development of enzyme inhibitors or receptor ligands.
- Organic Synthesis: A versatile building block for constructing complex heterocyclic compounds and natural product analogs.
- Catalyst Development: Potential ligand precursor for transition metal catalysts used in asymmetric synthesis.
Basic Information
| Product Name | n-(2-(Dimethylamino)Ethyl)-n-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinamide |
| CAS No. | 1092563-60-4 |
| Molecular Formula | C19H32BN3O3 |
| Molecular Weight | 361.29 g/mol |
| Synonyms | 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-[2-(dimethylamino)ethyl]-N-methylpyridine-2-carboxamide; N-[2-(Dimethylamino)ethyl]-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinamide; 2-Pyridinecarboxamide, N-[2-(dimethylamino)ethyl]-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol ester of 5-(N-methyl-N-[2-(dimethylamino)ethyl]carbamoyl)pyridine-2-boronic acid |
| EINECS | Contact for details |
Quality Control
Our n-(2-(Dimethylamino)Ethyl)-n-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural integrity suitable for research and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and opened under dry, inert conditions when possible to prevent moisture absorption and degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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