Description

2-(3,5-Dichloro-4-Fluorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its value lies in providing a stable, reactive handle for introducing the 3,5-dichloro-4-fluorophenyl moiety into complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used to construct complex molecules for novel herbicides, fungicides, and insecticides, leveraging the dichloro-fluorophenyl group.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as OLEDs or semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create labeled compounds or molecular probes for biological target identification and validation.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) serving diverse client projects.

Basic Information

Product Name	2-(3,5-Dichloro-4-Fluorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1092485-88-5
Molecular Formula	C12H14BCl2FO2
Molecular Weight	289.95 g/mol
Synonyms	3,5-Dichloro-4-fluorophenylboronic acid pinacol ester; (3,5-Dichloro-4-fluorophenyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(3,5-dichloro-4-fluorophenyl)-1,3,2-dioxaborolane; 2-(3,5-Dichloro-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3,5-Dichloro-4-fluorobenzeneboronic acid pinacol ester; Pinacol (3,5-dichloro-4-fluorophenyl)boronate; (3,5-Dichloro-4-fluorophenyl)BPin
EINECS	Contact for details

Quality Control

Our 2-(3,5-Dichloro-4-Fluorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analysis, including HPLC, NMR, and GC, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.