Description

3-[5-Fluoro-2-(Trifluoromethoxy)Phenyl]Propionicacid is a high-purity fluorinated aromatic propionic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique combination of fluorine and trifluoromethoxy substituents, which are instrumental for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in areas targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorinated phenyl moiety enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic display technologies.
• Organic Synthesis & Chemical Research: A versatile reagent for introducing the 5-fluoro-2-(trifluoromethoxy)phenyl group into more complex molecular architectures in academic and industrial R&D settings.
• Fluorine Chemistry Studies: Employed as a model compound for investigating the reactivity and properties of polyfluorinated aromatic systems.

Basic Information

Product Name	3-[5-Fluoro-2-(Trifluoromethoxy)Phenyl]Propionicacid
CAS No.	1092460-96-2
Molecular Formula	C10H6F4O3
Molecular Weight	250.15 g/mol
Synonyms	3-(5-Fluoro-2-(trifluoromethoxy)phenyl)propanoic acid; 5-Fluoro-2-(trifluoromethoxy)benzenepropanoic acid; 3-[5-Fluoro-2-(trifluoromethoxy)phenyl]propanoic acid; 1092460-96-2; α-Fluoro-ω-(trifluoromethoxy)phenylpropionic acid; 2-(Trifluoromethoxy)-5-fluorophenylpropionic acid; 3-(5-Fluoro-2-(trifluoromethoxyl)phenyl)propionic acid
EINECS	Contact for details

Quality Control

Every batch of 3-[5-Fluoro-2-(Trifluoromethoxy)Phenyl]Propionicacid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.