Description

5-Fluoro-2-(Trifluoromethoxy)Benzamide is a high-value fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both fluorine and trifluoromethoxy substituents, makes it a critical intermediate for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology.
• Agrochemical Synthesis: Used in the design and synthesis of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced electronic materials, including components for liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Organic Synthesis Building Block: Employed in cross-coupling reactions, amide bond formations, and other transformations to introduce complex fluorinated motifs into larger molecular frameworks.
• Chemical Research & Development: Utilized in academic and industrial R&D laboratories for exploring new synthetic methodologies and creating compound libraries for high-throughput screening.

Basic Information

Product Name	5-Fluoro-2-(Trifluoromethoxy)Benzamide
CAS No.	1092460-85-9
Molecular Formula	C8H5F4NO2
Molecular Weight	223.13 g/mol
Synonyms	5-Fluoro-2-(trifluoromethoxy)benzamide; 2-Trifluoromethoxy-5-fluorobenzamide; Benzamide, 5-fluoro-2-(trifluoromethoxy)-; 1092460-85-9; 5-Fluoro-α,α,α-trifluoro-o-anisamide; 5-Fluoro-2-(trifluoromethoxy)benzoic acid amide
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Trifluoromethoxy)Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.