Description

2-Bromo-5-oxazolecarboxaldehyde is a versatile and highly functionalized heterocyclic building block, essential for advanced organic synthesis. Its core value lies in the strategic combination of a reactive aldehyde group and a bromine substituent on the oxazole ring, enabling precise molecular construction. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinases and other enzymatic pathways.
• Agrochemical Synthesis: Used to construct novel fungicides, herbicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, fluorescent dyes, and photoactive polymers.
• Chemical Biology Probes: Useful for designing activity-based probes and molecular tags for studying biological processes.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse biaryl and conjugated systems.

Basic Information

Product Name	2-Bromo-5-oxazolecarboxaldehyde
CAS No.	1092352-00-5
Molecular Formula	C4H2BrNO2
Molecular Weight	175.97 g/mol
Synonyms	5-Bromooxazole-2-carboxaldehyde; 2-Bromooxazole-5-carboxaldehyde; 2-Bromo-1,3-oxazole-5-carbaldehyde; Oxazole, 2-bromo-5-formyl-; 5-Formyl-2-bromooxazole; (2-Bromooxazol-5-yl)methanal; 2-Bromo-5-oxazolecarbaldehyde
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-oxazolecarboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.