Description

4-(4,4,6-Trimethyl-1,3,2-Dioxaborinan-2-Yl)Benzonitrile is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is valued for its role as a key precursor in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific aryl nitrile and boronate ester functionalities.
• Material Science: Serves as a monomer or precursor for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Synthesis: Employed as a versatile reagent for introducing the benzonitrile moiety into complex molecules under mild conditions.
• Ligand and Catalyst Development: Useful in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Life Science Research: Acts as a probe or labeling agent in biochemical research and diagnostic assay development.

Basic Information

Product Name	4-(4,4,6-Trimethyl-1,3,2-Dioxaborinan-2-Yl)Benzonitrile
CAS No.	1092060-81-5
Molecular Formula	C14H18BNO2
Molecular Weight	243.11 g/mol
Synonyms	4-(4,4,6-Trimethyl-1,3,2-dioxaborinan-2-yl)benzonitrile; 2-(4-Cyanophenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane; Benzonitrile, 4-(4,4,6-trimethyl-1,3,2-dioxaborinan-2-yl)-; 4-(4,4,6-Trimethyl-1,3,2-dioxaborinane-2-yl)benzonitrile; 4-Cyanophenylboronic acid, pinacol ester analog (cyclic); 4-(Trimethyldioxaborinan-2-yl)benzonitrile; Boronate Ester of 4-Cyanophenylboronic Acid
EINECS	Contact for details

Quality Control

Our 4-(4,4,6-Trimethyl-1,3,2-Dioxaborinan-2-Yl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive and moisture-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.