Description

2-(4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Piperazin-1-Yl)Ethanol is a high-value, functionalized organoboron building block essential for modern synthetic chemistry. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds, enabling the construction of complex biaryl and heterobiaryl structures.
• Agrochemical Research: Used in the discovery and development of novel herbicides, fungicides, and insecticides that require specific piperazine-based architectures.
• Material Science: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and organic photovoltaics, where precise molecular design is crucial.
• Chemical Biology & Probe Development: Utilized for creating molecular probes and labeled compounds for biological target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-(4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Piperazin-1-Yl)Ethanol
CAS No.	1089686-81-6
Molecular Formula	C18H29BN2O3
Molecular Weight	332.25 g/mol
Synonyms	2-[4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazin-1-yl]ethanol; 2-(4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazin-1-yl)ethan-1-ol; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(2-hydroxyethyl)aniline piperazine derivative; 1089686-81-6; 2-(4-(4-Pinacolatoborylphenyl)piperazin-1-yl)ethanol; 4-(1-(2-Hydroxyethyl)piperazin-4-yl)phenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Piperazin-1-Yl)Ethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for sensitive coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.