Description

6-(2-Hydroxypropan-2-Yl)Pyridin-3-Ylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, enabling the introduction of the pyridine moiety.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials through cross-coupling reactions.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation reagents due to its boronic acid functionality.
• Catalyst & Ligand Development: Utilized as a starting material for synthesizing novel ligands and organometallic catalysts.
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis organizations (CSOs) and CDMOs serving the global life sciences market.

Basic Information

Product Name	6-(2-Hydroxypropan-2-Yl)Pyridin-3-Ylboronic Acid
CAS No.	1088496-42-7
Molecular Formula	C8H12BNO3
Molecular Weight	181.00 g/mol
Synonyms	3-Pyridineboronic acid, 6-(2-hydroxy-2-propanyl)-; 6-(2-Hydroxypropan-2-yl)pyridine-3-boronic acid; 6-(2-Hydroxy-2-propyl)pyridin-3-ylboronic acid; 6-(1-Hydroxy-1-methylethyl)pyridin-3-ylboronic acid; 5-Borono-2-(2-hydroxypropan-2-yl)pyridine; 2-(2-Hydroxypropan-2-yl)-5-pyridineboronic acid; (6-(2-Hydroxypropan-2-yl)pyridin-3-yl)boronic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 6-(2-Hydroxypropan-2-Yl)Pyridin-3-Ylboronic Acid is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to guarantee identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, supporting your regulatory and quality assurance requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.