Description

3-Nitroisonicotinaldehyde Dihydrate is a specialized nitro-substituted pyridine derivative that serves as a high-value synthetic intermediate. This compound is critical for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for its role in heterocyclic and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides due to its bioactive nitro and aldehyde functional groups.
• Ligand Synthesis: Serves as a precursor for creating complex chelating ligands used in catalysis and material science.
• Fine Chemical Production: Employed in the multi-step synthesis of dyes, pigments, and other performance chemicals.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and heterocyclic chemistry within university and corporate laboratories.

Basic Information

Product Name	3-Nitroisonicotinaldehyde Dihydrate
CAS No.	1087734-75-5
Molecular Formula	C6H4N2O3 · 2H2O
Molecular Weight	188.13 g/mol (Anhydrous basis: 152.11 g/mol)
Synonyms	3-Nitro-4-pyridinecarboxaldehyde Dihydrate; 4-Formyl-3-nitropyridine Dihydrate; Isonicotinaldehyde, 3-nitro-, dihydrate; 3-Nitroisonicotinaldehyde Hydrate; 3-Nitro-4-formylpyridine Dihydrate; 3-Nitro-4-pyridylcarboxaldehyde Dihydrate; 3-Nitro-4-pyridinealdehyde Dihydrate
EINECS	Contact for details

Quality Control

Every batch of 3-Nitroisonicotinaldehyde Dihydrate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency meet the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	16.0% - 20.0% (Theoretical for dihydrate: ~19.1%)
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.