Description

tert-Butyl 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenethylcarbamate is a high-purity, protected boronic ester derivative designed for advanced synthetic chemistry. This compound is a critical building block in the synthesis of complex molecules, offering a stable and reactive handle for Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for constructing active pharmaceutical ingredients (APIs) and other high-value intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds in complex molecule assembly.
• Peptidomimetic Research: Used in the construction of peptide-like molecules for drug discovery and biochemical studies.
• Material Science: A potential monomer or intermediate for creating functional polymers and advanced organic materials.
• Agrochemical Synthesis: Employed in the research and development of new, more effective crop protection agents.
• Academic & Contract Research: Essential for methodological development and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	tert-Butyl 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenethylcarbamate
CAS No.	1086600-36-3
Molecular Formula	C19H30BNO4
Molecular Weight	347.26 g/mol
Synonyms	Boc-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenethylamine; N-Boc-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenethylamine; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenethylcarbamic acid tert-butyl ester; tert-Butyl N-[2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl]carbamate; 1086600-36-3; Boc-protected boronic ester phenethylamine.
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenethylcarbamate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and production. All materials undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.