Description

5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazole is a high-purity organoboron building block, specifically a thiazole-substituted boronic ester, essential for modern synthetic chemistry. Its core value lies in enabling efficient, palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex heterocyclic scaffolds. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those containing thiazole or fused heterocyclic cores with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for studying biological processes and target engagement.
• Academic & Contract Research: A vital reagent for methodology development and exploring new synthetic routes in university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis & Scale-up: Provides a reliable starting point for custom synthesis projects, from milligram-scale research to kilogram-scale process development.

Basic Information

Item	Details
Product Name	5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazole
CAS No.	1086111-09-2
Molecular Formula	C9H14BNO2S
Molecular Weight	211.09 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole; Thiazol-5-ylboronic acid pinacol ester; 5-Thiazoleboronic acid pinacol ester; 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-thiazole; Pinacol 5-thiazolylboronate; 5-Boronothiazole pinacol ester
EINECS	Contact for details

Quality Control

Our 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is analyzed using advanced techniques including HPLC, NMR (¹H and ¹³C), and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.