Description

B-[1-(2-Hydroxyethyl)-1H-Pyrazol-4-Yl]Boronic Acid is a high-value boronic acid derivative, a critical building block in modern synthetic chemistry. Its core value lies in its dual functionality, combining a reactive boronic acid group with a pyrazole heterocycle and a pendant hydroxyethyl chain, making it an exceptionally versatile intermediate for cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require precise molecular scaffolds for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used to construct complex heterocyclic structures found in advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or linker for creating functional polymers, organic electronic materials, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the development of bioconjugation reagents and activity-based probes for studying biological pathways.
• Ligand Synthesis: Acts as a starting material for preparing sophisticated polydentate ligands used in catalysis and metal complexation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates under cGMP conditions.

Basic Information

Product Name	B-[1-(2-Hydroxyethyl)-1H-Pyrazol-4-Yl]Boronic Acid
CAS No.	1086063-70-8
Molecular Formula	C5H9BN2O3
Molecular Weight	155.95 g/mol
Synonyms	[1-(2-Hydroxyethyl)-1H-pyrazol-4-yl]boronic acid; (1-(2-Hydroxyethyl)-1H-pyrazol-4-yl)boronic acid; 4-Borono-1-(2-hydroxyethyl)pyrazole; 1-(2-Hydroxyethyl)-4-pyrazoleboronic acid; 1H-Pyrazole-4-boronic acid, 1-(2-hydroxyethyl)-; B-(1-(2-Hydroxyethyl)-1H-pyrazol-4-yl)boronic acid; NSC 797084
EINECS	Contact for details

Quality Control

Our B-[1-(2-Hydroxyethyl)-1H-Pyrazol-4-Yl]Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with full analytical data are provided for every shipment. We support development and commercial projects with material suitable for research use through to cGMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.