Description

n-[2-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3-Pyridinyl]-Benzenesulfonamide is a high-purity, advanced pharmaceutical intermediate featuring a key boronic ester functional group. This compound is of significant value in modern organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, which are pivotal for constructing complex biaryl structures. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex heterocyclic and biaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reagent: The pinacol boronate ester group serves as a versatile handle for palladium-catalyzed carbon-carbon bond formation with aryl halides.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides that require specific aryl-pyridine architectures.
• Material Science: Potential precursor for creating organic electronic materials and ligands for catalytic systems.
• Chemical Biology & Medicinal Chemistry: Employed in the synthesis of molecular probes and tool compounds for target validation and drug discovery programs.

Basic Information

Product Name	n-[2-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3-Pyridinyl]-Benzenesulfonamide
CAS No.	1083326-67-3
Molecular Formula	C18H23BN2O5S
Molecular Weight	390.26 g/mol
Synonyms	Benzenesulfonamide, N-[2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinyl]-; 3-(N-Phenylsulfamoyl)-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(phenylsulfonyl)pyridin-3-amine; 1083326-67-3; 3-Pyridinylbenzenesulfonamide boronic ester derivative
EINECS	Contact for details

Quality Control

Our n-[2-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3-Pyridinyl]-Benzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.