Description

5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine-3-Sulfonamide is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. This compound is valued for its unique molecular architecture, combining a pyridine-sulfonamide core with a pinacol boronate ester functional group, which is critical for modern synthetic methodologies. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boron-containing coupling partner for the synthesis of biaryl and heterobiaryl structures prevalent in drug discovery.
• Pharmaceutical Intermediate: Used in the research and development of potential therapeutic agents, particularly those targeting enzymes where the sulfonamide moiety acts as a pharmacophore.
• Agrochemical Synthesis: Employed in creating novel pesticides and herbicides, leveraging the pyridine ring for bioactivity.
• Material Science Research: Acts as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein function.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise functionalization of the pyridine ring system.

Basic Information

Product Name	5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine-3-Sulfonamide
CAS No.	1083326-26-4
Molecular Formula	C11H17BN2O4S
Molecular Weight	284.14 g/mol
Synonyms	3-Sulfamoyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-sulfonamide; Pyridine-3-sulfonamide, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(Pinacolatoboryl)pyridine-3-sulfonamide; 3-Pyridinesulfonamide, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(Pinacol boronate)pyridine-3-sulfonamide
EINECS	Contact for details

Quality Control

Our 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine-3-Sulfonamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.