Description

1-Methyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Imidazole is a high-value organoboron building block, specifically a pinacol-protected imidazole boronic ester, essential for modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for the synthesis of novel drug candidates, functional ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing imidazole heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel fungicides, herbicides, and plant growth regulators.
• Material Science: Enables the creation of functional organic materials, including organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of enzyme inhibitors or molecular probes.
• Catalyst Ligand Precursor: Used to synthesize N-heterocyclic carbene (NHC) ligands and other complex ligands for transition metal catalysis.
• Academic & Contract Research: A vital reagent for methodology development and complex molecule synthesis in academic and industrial research laboratories.

Basic Information

Product Name	1-Methyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Imidazole
CAS No.	1083180-01-1
Molecular Formula	C10H17BN2O2
Molecular Weight	208.07 g/mol
Synonyms	1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-imidazole; 1-Methyl-4-(pinacolatoboryl)imidazole; 1-Methyl-4-imidazoleboronic acid pinacol ester; 1-Methyl-1H-imidazole-4-boronic acid pinacol ester; 4-Borono-1-methyl-1H-imidazole pinacol ester; 1-Methylimidazole-4-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 1-Methyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Imidazole adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. All materials undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation, and separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.