Description

Thiazol-4-Ylboronic Acid Pinacol Ester is a high-purity organoboron building block essential for modern synthetic chemistry. This compound is a critical reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel thiazole-containing drug candidates in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with thiazole motifs.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, via cross-coupling polymerization.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of chemical probes and inhibitors.
• Academic & Contract Research: A fundamental reagent for methodology development and complex molecule synthesis in research laboratories.
• Scale-up API Manufacturing: Supports the transition from laboratory-scale discovery to commercial-scale production of target molecules.

Basic Information

Product Name	Thiazol-4-Ylboronic Acid Pinacol Ester
CAS No.	1083180-00-0
Molecular Formula	C11H16BNO2S
Molecular Weight	237.13 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; Thiazol-4-ylboronic acid pinacol ester; 2-(Thiazol-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Thiazoleboronic Acid Pinacol Ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole; Thiazole-4-boronic Acid Pinacol Ester; 4-Boronothiazole Pinacol Ester
EINECS	Contact for details

Quality Control

Our Thiazol-4-Ylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency for sensitive coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are provided for each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive (store away from light) and should be kept under an inert atmosphere for long-term storage to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.