Description

5-Fluoro-2-Methoxypyridine-3-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its value lies in its stability and reactivity, making it an essential reagent for the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex organic molecules.

Application

• Key intermediate in the Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl systems.
• Building block for the synthesis of pharmaceutical candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Precursor in the development of agrochemicals, such as herbicides and fungicides with novel modes of action.
• Used in material science for creating organic electronic materials and functionalized ligands for catalysis.
• Essential reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	5-Fluoro-2-Methoxypyridine-3-Boronic Acid Pinacol Ester
CAS No.	1083168-95-9
Molecular Formula	C₁₂H₁₇BFNO₃
Molecular Weight	253.08 g/mol
Synonyms	5-Fluoro-2-methoxypyridine-3-boronic acid pinacol ester; (5-Fluoro-2-methoxypyridin-3-yl)boronic acid pinacol ester; 3-Borono-5-fluoro-2-methoxypyridine pinacol ester; 5-Fluoro-2-methoxy-3-pyridineboronic acid pinacol ester; Pinacol (5-fluoro-2-methoxypyridin-3-yl)boronate; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-fluoro-2-methoxypyridine; 1083168-95-9
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methoxypyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.