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Dioxaborolan-2-Yl)-Pyridine CAS NO 1083168-94-8


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CAS No.:1083168-94-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dioxaborolan-2-Yl)-Pyridine is a specialized organoboron reagent featuring a pyridine moiety and a pinacol boronate ester group. This compound is a critical building block in modern synthetic chemistry, enabling efficient cross-coupling reactions for the construction of complex molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery, catalyst development, and the synthesis of functional organic compounds.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and boronic acid derivatives.
  • Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing pyridine or biphenyl structures.
  • Agrochemical Compound Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides.
  • Ligand and Catalyst Preparation: Serves as a precursor for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
  • Material Science Research: Used in the synthesis of organic semiconductors, light-emitting materials, and other functional polymers.
  • Chemical Biology Probes: Facilitates the labeling and study of biomolecules through bioorthogonal chemistry.

Basic Information

Product Name Dioxaborolan-2-Yl)-Pyridine
CAS No. 1083168-94-8
Molecular Formula C11H14BNO2
Molecular Weight 203.05 g/mol
Synonyms 2-(Pyridin-2-yl)-1,3,2-dioxaborolane; 2-(2-Pyridinyl)-1,3,2-dioxaborolane; 2-(Pyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (common mis-assignment, provided for clarity); Pyridine-2-boronic acid pinacol ester; 2-Pyridinylboronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Pyridylboronic Acid Pinacol Ester
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Quality Control

Our Dioxaborolan-2-Yl)-Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to maintain product integrity and prevent moisture absorption.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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