Description

2,3-Dimethoxypyridine-5-Boronic Acid,Pinacol Ester is a high-value boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized in the development of molecular probes and tools for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2,3-Dimethoxypyridine-5-Boronic Acid,Pinacol Ester
CAS No.	1083168-92-6
Molecular Formula	C13H20BNO4
Molecular Weight	265.12 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dimethoxypyridine; 2,3-Dimethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2,3-Dimethoxypyridin-5-ylboronic acid pinacol ester; 2,3-Dimethoxy-5-pyridineboronic acid pinacol ester; 1083168-92-6; AKOS010703054; BRN 15412745
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dimethoxypyridine-5-Boronic Acid,Pinacol Ester is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high purity and lot-to-lot consistency to meet the stringent requirements of research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles via validated methods such as NMR, HPLC, and GC.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.