Description

1-[2-(Methylsulfonyl)Ethyl]-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester is a sophisticated boronic ester derivative, a key building block in modern pharmaceutical and agrochemical research. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex carbon-carbon bonds. This high-purity intermediate is essential for medicinal chemists and process development scientists in the pharmaceutical industry, particularly for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel small-molecule drug candidates, especially in oncology, CNS, and anti-infective therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boron-containing coupling partner for constructing biaryl and heterobiaryl structures central to many modern pharmaceuticals.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its ability to introduce complex pyridine-based motifs.
• Material Science: Potential building block for creating advanced organic electronic materials and functional polymers.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of target molecules.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	1-[2-(Methylsulfonyl)Ethyl]-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester
CAS No.	1083168-89-1
Molecular Formula	C15H22BNO5S
Molecular Weight	339.22 g/mol
Synonyms	6-Oxo-1-[2-(methylsulfonyl)ethyl]-1,6-dihydropyridine-3-boronic acid pinacol ester; 3-Pyridineboronic acid, 1,2-dihydro-1-[2-(methylsulfonyl)ethyl]-6-oxo-, 1,1-dimethylethyl ester; 1-(2-Methanesulfonylethyl)-6-oxo-1,6-dihydropyridin-3-ylboronic acid pinacol ester; 1083168-89-1; Boronic acid, B-[1-[2-(methylsulfonyl)ethyl]-6-oxo-1,6-dihydro-3-pyridinyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 1-[2-(Methylsulfonyl)Ethyl]-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.