Description

2-Methoxy-3-Methyl-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the efficient and precise construction of complex molecular architectures, which is critical for developing new active compounds. This advanced intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for drug discovery and the synthesis of novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used to construct complex pyridine-based scaffolds for developing new generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs (Organic Light-Emitting Diodes) and other functional polymers.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Item	Details
Product Name	2-Methoxy-3-Methyl-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine
CAS No.	1083168-83-5
Molecular Formula	C13H20BNO3
Molecular Weight	249.12 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methoxy-3-methylpyridine; 2-Methoxy-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Methyl-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Methoxy-3-methylpyridine-5-boronic acid pinacol ester; Pyridine, 2-methoxy-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1083168-83-5
EINECS	Contact for details

Quality Control

Every batch of 2-Methoxy-3-Methyl-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A detailed Certificate of Analysis (COA) including HPLC purity, NMR confirmation, and residual solvent analysis is supplied with each shipment to guarantee reproducible performance and supply chain traceability for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) for long-term storage and when dispensing to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (H-NMR)	Conforms to structure
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.