Description

7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Isoquinoline is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and advanced materials research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the isoquinoline scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science Research: Serves as a precursor in the development of organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and other functional organic materials.
• Chemical Biology & Probe Development: Utilized for creating labeled compounds and molecular probes for diagnostic and biochemical research applications.
• Academic & Contract Research: A critical reagent for methodology development and complex molecule synthesis in academic laboratories and CROs (Contract Research Organizations).
• Catalyst Ligand Precursor: Can be used to synthesize novel ligand systems for transition metal catalysis.

Basic Information

Product Name	7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Isoquinoline
CAS No.	1082947-07-6
Molecular Formula	C₁₅H₂₀BNO₂
Molecular Weight	257.14 g/mol
Synonyms	7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline; Isoquinoline-7-boronic acid pinacol ester; 7-(Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline; 7-Isoquinolineboronic Acid Pinacol Ester; 7-Boronophenylisoquinoline Pinacol Ester; B-(7-Isoquinolinyl)boronic Acid Pinacol Ester; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-isoquinoline
EINECS	Contact for details

Quality Control

Our 7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Isoquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, critical for sensitive cross-coupling reactions. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management standards, and our processes are designed to meet the stringent requirements of pharmaceutical development (following ICH Q7 guidelines) and advanced material synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	≥95.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.