Description

1-(4-Fluorophenylsulfonyl)Piperidin-4-Ol is a high-purity (98+%) sulfonyl piperidine derivative with the molecular formula C11H14FNO3S and a molecular weight of 259.30, serving as a critical pharmaceutical intermediate and organic building block for advanced synthesis. Its unique structure, featuring both a fluorophenylsulfonyl group and a piperidinol moiety, makes it a versatile scaffold for medicinal chemistry research and the development of bioactive molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and enzyme inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Intermediate in the research and production of novel herbicides, fungicides, or insecticides.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and protein function.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce specific fluorinated sulfonamide functionalities into complex molecules.
• Academic Research: Used in universities and research institutes for methodological development and exploring new chemical reactions.

Basic Information

Product Name	1-(4-Fluorophenylsulfonyl)Piperidin-4-Ol
CAS No.	1082928-80-0
Molecular Formula	C11H14FNO3S
Molecular Weight	259.30 g/mol
Synonyms	4-Hydroxy-1-(4-fluorophenylsulfonyl)piperidine; 1-[(4-Fluorophenyl)sulfonyl]-4-piperidinol; 4-Piperidinol, 1-[(4-fluorophenyl)sulfonyl]-; 1-(4-Fluorobenzenesulfonyl)piperidin-4-ol; 4-Hydroxy-1-(4-fluorobenzenesulfonyl)piperidine; 1-(p-Fluorophenylsulfonyl)-4-hydroxypiperidine; 4-Fluoro-N-(4-hydroxypiperidin-1-yl)sulfonyl]benzene
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenylsulfonyl)Piperidin-4-Ol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure the specified purity of 98+% and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.