Description

(2-Fluoro-Phenyl)-(4-Hydroxy-Piperidin-1-Yl)-Methanone, 98+% C12H14FNO2, Mw: 223.25 is a high-purity, fluorinated piperidine derivative serving as a critical pharmaceutical intermediate and research chemical. Its molecular structure, featuring a fluorinated aromatic ring and a hydroxypiperidine moiety, makes it a valuable building block for medicinal chemistry, particularly in the development of central nervous system (CNS) active compounds and enzyme inhibitors. This compound is essential for R&D laboratories and chemical synthesis units focused on creating novel bioactive molecules for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Employed in pharmacological research to study receptor interactions and enzyme inhibition mechanisms.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to introduce the fluorophenyl and N-hydroxypiperidine carbonyl fragments into more complex molecules.
• Agrochemical Research: Potential intermediate in the synthesis of advanced crop protection agents and pesticides.
• Material Science: Investigated as a monomer or additive for specialty polymers with unique properties.

Basic Information

Product Name	(2-Fluoro-Phenyl)-(4-Hydroxy-Piperidin-1-Yl)-Methanone
CAS No.	1082804-68-9
Molecular Formula	C12H14FNO2
Molecular Weight	223.25 g/mol
Synonyms	1-(2-Fluorobenzoyl)-4-hydroxypiperidine; 4-Hydroxy-1-(2-fluorobenzoyl)piperidine; (2-Fluorophenyl)(4-hydroxypiperidin-1-yl)methanone; 4-Hydroxy-N-(2-fluorophenyl)piperidine-1-carboxamide; 1082804-68-9; AKOS005714623; 2-Fluoro-N-(4-hydroxypiperidin-1-yl)benzamide; F2198-1088
EINECS	Contact for details

Quality Control

Our (2-Fluoro-Phenyl)-(4-Hydroxy-Piperidin-1-Yl)-Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the specified 98+% purity grade and is free from critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.