Description

[1-(2-Hydroxy-2-Methyl-Propyl)Pyrazol-4-Yl]Boronic Acid Pinacol Ester is a high-value, organoboron building block crucial for modern synthetic chemistry. This compound matters as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecules. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in modern herbicides, fungicides, and insecticides.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers, OLED materials, and liquid crystals.
• Chemical Biology & Diagnostics: Employed in the creation of molecular probes, sensors, and bioconjugates for research and diagnostic applications.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel bidentate or tridentate ligands used in homogeneous catalysis.
• Academic & Contract Research: An essential reagent for methodology development and complex molecule synthesis in research laboratories worldwide.

Basic Information

Product Name	[1-(2-Hydroxy-2-Methyl-Propyl)Pyrazol-4-Yl]Boronic Acid Pinacol Ester
CAS No.	1082503-77-2
Molecular Formula	C₁₃H₂₃BN₂O₃
Molecular Weight	266.15 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-hydroxy-2-methylpropyl)-1H-pyrazole; 1-(2-Hydroxy-2-methylpropyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; (1-(2-Hydroxy-2-methylpropyl)-1H-pyrazol-4-yl)boronic acid pinacol ester; 1-(2-Hydroxy-2-methylpropyl)-1H-pyrazole-4-boronic acid pinacol ester; Pyrazole-4-boronic acid pinacol ester derivative; B-[1-(2-Hydroxy-2-methylpropyl)-1H-pyrazol-4-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our [1-(2-Hydroxy-2-Methyl-Propyl)Pyrazol-4-Yl]Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening the primary container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.