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4-(Oxazol-2-Yl)Phenylboronic Acid CAS NO 1082066-51-0


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CAS No.:1082066-51-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-(Oxazol-2-Yl)Phenylboronic Acid is a specialized organoboron compound featuring a phenylboronic acid moiety linked to an oxazole heterocycle. This unique bifunctional structure makes it a valuable building block in modern synthetic chemistry, particularly for cross-coupling reactions. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the synthesis of complex molecules and advanced intermediates.

Application

  • Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in active pharmaceutical ingredients (APIs).
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
  • Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
  • Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and sensors that leverage boronic acid-diol interactions.
  • Ligand Synthesis for Catalysis: Used to create sophisticated ligands for transition metal catalysts used in asymmetric synthesis.
  • Academic & Contract Research: A valuable reagent for methodological development and complex molecule synthesis in academic and industrial research laboratories.

Basic Information

Product Name 4-(Oxazol-2-Yl)Phenylboronic Acid
CAS No. 1082066-51-0
Molecular Formula C9H8BNO3
Molecular Weight 189.98 g/mol
Synonyms [2-(4-Boronophenyl)oxazole]; 4-(1,3-Oxazol-2-yl)benzeneboronic acid; (4-(Oxazol-2-yl)phenyl)boronic acid; 2-(4-Boronophenyl)oxazole; 4-(Oxazol-2-yl)phenylboronic acid pinacol ester (protected form); B-[4-(1,3-Oxazol-2-yl)phenyl]boronic acid
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Quality Control

Our 4-(Oxazol-2-Yl)Phenylboronic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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