Description

4-Fluoro-5-Nitro 1H-Indazole (CAS NO 1082041-35-7) is a high-value, multi-functional heterocyclic building block essential for modern pharmaceutical and agrochemical research. Its core value lies in the strategic placement of fluorine and nitro groups on the indazole scaffold, enabling precise molecular modifications to develop novel active compounds. This intermediate is critically needed by R&D chemists and process development scientists in the life sciences sector for creating new drug candidates, particularly in oncology and CNS therapeutic areas, as well as advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated indazole core.
• Material Science: Serves as a precursor for advanced organic electronic materials and functional dyes.
• Chemical Biology: Employed as a molecular probe or tag in biochemical assays and diagnostic development.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs for client-specific molecule libraries.

Basic Information

Product Name	4-Fluoro-5-Nitro 1H-Indazole
CAS No.	1082041-35-7
Molecular Formula	C7H4FN3O2
Molecular Weight	181.12 g/mol
Synonyms	4-Fluoro-5-nitro-1H-indazole; 1H-Indazole, 4-fluoro-5-nitro-; 5-Nitro-4-fluoroindazole; 4-Fluoro-5-nitroindazole; 1082041-35-7; AKOS006361889; ZINC000095515756; SCHEMBL15450427
EINECS	Contact for details

Quality Control

Our 4-Fluoro-5-Nitro 1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.