Description

4-Iodo-7-Azaindole-3-Carbaldehyde is a versatile and high-value heterocyclic building block, specifically a halogenated azaindole derivative. This compound is critical for medicinal chemistry research and pharmaceutical development, offering a reactive aldehyde group and a halogenated aromatic system for diverse synthetic modifications. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its modifiable scaffold.
• Agrochemical Development: Employed in creating novel active ingredients for crop protection products.
• Chemical Biology Probes: Acts as a starting material for developing fluorescent tags or activity-based probes for biological target identification.
• Material Science: Potential building block for organic electronic materials and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).

Basic Information

Product Name	4-Iodo-7-Azaindole-3-Carbaldehyde
CAS No.	1082040-17-2
Molecular Formula	C8H5IN2O
Molecular Weight	272.04 g/mol
Synonyms	4-Iodo-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde; 4-Iodo-7-azaindole-3-carboxaldehyde; 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-iodo-; 4-Iodo-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde; 4-Iodo-7-aza-1H-indole-3-carbaldehyde; 1082040-17-2; 4-Iodo-7-azaindole-3-aldehyde
EINECS	Contact for details

Quality Control

Our 4-Iodo-7-Azaindole-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.