Description

3-(2-Fluorophenyl)Cyclobutanone is a specialized fluorinated cyclobutanone derivative, a key building block in advanced organic synthesis. This compound is valued for its unique structural motif, which combines the constrained geometry of a cyclobutane ring with the electronic influence of an ortho-fluorinated aromatic system. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorinated cyclobutanone core can impart favorable biological activity and metabolic stability.
• Material Science: Acts as a monomer or cross-linking agent in the research of advanced polymers with specific thermal or optical properties.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis, leveraging the steric and electronic properties of the fluorophenyl group.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including ring-expansion and photochemical reactions.

Basic Information

Product Name	3-(2-Fluorophenyl)Cyclobutanone
CAS No.	1080636-31-2
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	2-Fluorophenyl Cyclobutanone; 3-(2-Fluorophenyl)cyclobutan-1-one; 1-(2-Fluorophenyl)cyclobutan-3-one; Cyclobutanone, 3-(2-fluorophenyl)-; 2-Fluorobenzenecyclobutanone; (2-Fluorophenyl)cyclobutanone; 1080636-31-2 (CAS)
EINECS	Contact for details

Quality Control

Our 3-(2-Fluorophenyl)Cyclobutanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.