Description

Dioxaborolan-2-Yl)-Pyridine is a specialized organoboron compound featuring a pyridine ring linked to a dioxaborolane moiety. This structure is critical for its role as a versatile building block in modern synthetic chemistry, particularly in cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require high-purity intermediates for complex synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, including active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, especially in creating biaryl and heterobiaryl structures common in modern therapeutics.
• Material Science Research: Serves as a precursor for constructing organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Agrochemical Synthesis: Employed in the development of new agrochemicals where the pyridine-boronate complex introduces specific functional groups.
• Ligand and Catalyst Development: Utilized to create novel ligands for transition metal catalysts or as a component in catalyst systems.
• Chemical Biology Probes: Acts as a handle for bioconjugation and labeling in probe development due to its selective reactivity.

Basic Information

Product Name	Dioxaborolan-2-Yl)-Pyridine
CAS No.	1080028-73-4
Molecular Formula	C9H10BNO2
Molecular Weight	174.99 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pyridine-2-boronic acid pinacol ester; 2-Pyridinylboronic acid pinacol ester; 2-(Pyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Pyridylboronic Acid Pinacol Ester; 2-Pyridyl MIDA Boronate (related precursor); 2-PyBpin
EINECS	Contact for details

Quality Control

Every batch of Dioxaborolan-2-Yl)-Pyridine is produced and tested under strict quality management systems to ensure consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	≥95.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.