Description

(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Methanol is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile intermediate for constructing complex molecules via cross-coupling reactions, enabling the development of novel pharmaceuticals and advanced materials. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality synthetic intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to create novel pyridine-based compounds for crop protection agents, including fungicides and herbicides.
• Material Science Research: Serves as a building block for constructing organic ligands in metal-organic frameworks (MOFs) and for developing functional polymers with specific electronic properties.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and probes for studying biological pathways and target engagement.
• Liquid Crystal & OLED Materials: A valuable intermediate for synthesizing advanced organic electronic materials used in displays and lighting.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom synthesis projects and library generation for high-throughput screening.

Basic Information

Product Name	(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Methanol
CAS No.	1078575-71-9
Molecular Formula	C13H20BNO3
Molecular Weight	249.12 g/mol
Synonyms	2-Pyridinemethanol, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; (5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)methanol; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-methanol; 2-(Hydroxymethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol (5-(hydroxymethyl)pyridin-2-yl)boronate
EINECS	Contact for details

Quality Control

Our (5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.