Description

5-(tert-Butoxycarbonyl)-3A,4,5,6,7,7A-Hexahydrothieno[3,2-C]Pyridin-2-Ylboronic Acid is a sophisticated, high-purity boronic acid derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in modern pharmaceutical research, enabling the construction of complex molecular architectures through reliable cross-coupling reactions. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds with potential therapeutic activity.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a versatile boron reagent for forming carbon-carbon bonds, essential for constructing drug-like molecules.
• Medicinal Chemistry & Drug Discovery: Used in lead optimization and library synthesis to explore new chemical space and develop candidate drugs.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection products.
• Chemical Biology Probes: Useful for creating labeled compounds or probes to study biological pathways and target engagement.
• Process Chemistry Development: Serves as a reliable intermediate for scaling up synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	5-(tert-Butoxycarbonyl)-3A,4,5,6,7,7A-Hexahydrothieno[3,2-C]Pyridin-2-Ylboronic Acid
CAS No.	1078151-34-4
Molecular Formula	C12H18BNO4S
Molecular Weight	283.15 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3a,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridine-5-carboxylic acid tert-butyl ester; tert-Butyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3a,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridine-5-carboxylate; 5-Boc-3a,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridine-2-boronic acid; 5-(tert-Butoxycarbonyl)-3a,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridin-2-ylboronic acid; BOC-Protected Hexahydrothienopyridine Boronic Acid; 1078151-34-4
EINECS	Contact for details

Quality Control

Our production of 5-(tert-Butoxycarbonyl)-3A,4,5,6,7,7A-Hexahydrothieno[3,2-C]Pyridin-2-Ylboronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. All materials undergo rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.