Description

n-(n-Boc-Piperidino)Pyrazole-4-Carboxaldehyde is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine and a reactive aldehyde group. This compound is critical for the efficient synthesis of complex molecules, particularly in medicinal chemistry and drug discovery pipelines. It is primarily utilized by research institutions and pharmaceutical manufacturers developing novel active pharmaceutical ingredients (APIs) and small molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker component in the design of bifunctional degrader molecules.
• Chemical Biology Probes: Employed in the creation of labeled compounds for studying biological processes and target engagement.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and methodology development.

Basic Information

Product Name	n-(n-Boc-Piperidino)Pyrazole-4-Carboxaldehyde
CAS No.	1076224-00-4
Molecular Formula	C14H21N3O3
Molecular Weight	279.34 g/mol
Synonyms	1-Boc-4-(4-Formyl-1H-pyrazol-1-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(4-formyl-1H-pyrazol-1-yl)piperidine; 4-(1H-Pyrazol-4-ylcarboxaldehyde)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-(4-formyl-1H-pyrazol-1-yl)piperidine-1-carboxylate; N-Boc-4-(4-formylpyrazol-1-yl)piperidine; 1-Boc-4-(4-formylpyrazol-1-yl)piperidine; Boc-Pip-Pyrazole-CHO
EINECS	Contact for details

Quality Control

Our n-(n-Boc-Piperidino)Pyrazole-4-Carboxaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.