Description

Ethyl Difluorothioacetate is a specialized fluorinated building block of significant interest in advanced organic synthesis. Its unique molecular structure, featuring both fluorine and sulfur functionalities, makes it a valuable precursor for constructing complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides where the difluoromethylthio group can impart unique biological activity.
• Material Science Research: Serves as a precursor for introducing fluorinated thioester groups into polymers or advanced materials to modify surface properties.
• Organic Synthesis Building Block: Employed in various name reactions and coupling chemistries to introduce the -SCF2CO- moiety into target molecules.
• Ligand and Catalyst Development: Useful in the synthesis of specialized ligands for catalysis, particularly in asymmetric synthesis.

Basic Information

Product Name	Ethyl Difluorothioacetate
CAS No.	1076198-05-4
Molecular Formula	C4H6F2OS
Molecular Weight	140.15 g/mol
Synonyms	Ethyl 2,2-difluorothioacetate; Acetic acid, 2,2-difluoro-, thio-, S-ethyl ester; S-Ethyl 2,2-difluorothioacetate; 2,2-Difluorothioacetic Acid S-Ethyl Ester; Difluorothioacetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl Difluorothioacetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.