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4-Ethylphenylboronic Acid Pinacol Ester CAS NO 1075719-87-7
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CAS No.:1075719-87-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-Ethylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex organic molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery, catalyst development, and fine chemical synthesis.
Application
- Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and this boronic ester, crucial for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs).
- Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly in creating complex, functionalized aromatic scaffolds.
- Agrochemical Product Development: Employed in the synthesis of advanced herbicides, fungicides, and insecticides that require specific aryl-ethyl substitutions.
- Material Science & OLED Development: Acts as a precursor for creating organic electronic materials, including charge-transport layers and emissive materials in OLED displays.
- Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for transition metal catalysts used in asymmetric synthesis.
- Custom Fine Chemical Manufacturing: Serves as a versatile starting material for contract research organizations (CROs) and custom synthesis facilities.
Basic Information
| Product Name | 4-Ethylphenylboronic Acid Pinacol Ester |
| CAS No. | 1075719-87-7 |
| Molecular Formula | C14H21BO2 |
| Molecular Weight | 232.13 g/mol |
| Synonyms | 4-Ethylbenzeneboronic Acid Pinacol Ester; 2-(4-Ethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (4-Ethylphenyl)boronic Acid Pinacol Ester; Pinacol 4-Ethylphenylboronate; 4-Ethylphenyl-Bpin; B-(4-Ethylphenyl)boronic Acid Pinacol Ester; 1-Ethyl-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene |
| EINECS | Contact for details |
Quality Control
Our 4-Ethylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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