Description

Boc-6-Amino-5-Methylpyridine-3-Boronic Acid Pinacol Ester CAS NO 1075249-37-4 is a high-value, protected boronic ester building block designed for advanced organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in creating complex heterocyclic cores prevalent in modern drug discovery.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific pyridine-based structures.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and novel polymers via cross-coupling methodologies.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the synthesis of molecular probes for studying biological systems.
• Library Synthesis for Drug Screening: Enables the rapid, parallel construction of diverse compound libraries for high-throughput screening in medicinal chemistry campaigns.
• Process Chemistry & Scale-up: Provides a stable, handleable form of the boronic acid functionality for optimized large-scale manufacturing processes.

Basic Information

Product Name	Boc-6-Amino-5-Methylpyridine-3-Boronic Acid Pinacol Ester
CAS No.	1075249-37-4
Molecular Formula	C17H27BN2O4
Molecular Weight	334.22 g/mol
Synonyms	tert-Butyl (5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate; 2-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-methyl-3-pyridineboronic acid pinacol ester; N-Boc-6-Amino-5-methylpyridine-3-boronic acid pinacol ester; Boc-6-Amino-5-methyl-3-pyridylboronic acid pinacol ester; (2-((tert-Butoxycarbonyl)amino)-5-methylpyridin-3-yl)boronic acid pinacol ester; 1075249-37-4; Boc-Protected 6-Amino-5-methylpyridine-3-boronic ester
EINECS	Contact for details

Quality Control

Our Boc-6-Amino-5-Methylpyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a controlled, dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.