Description

4-(Trifluoromethyl)Cyclohexane-1-Carbaldehyde is a versatile fluorinated aldehyde building block, offering unique reactivity and physicochemical properties due to the electron-withdrawing trifluoromethyl group. This compound is essential for introducing the trifluoromethylcyclohexyl moiety into target molecules, a key structural feature for modulating lipophilicity, metabolic stability, and biological activity. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances compound efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed as a monomer or cross-linking agent to create specialty polymers with enhanced chemical resistance and specific optical properties.
• Catalyst & Ligand Development: Used to synthesize novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Fluorine Chemistry Research: A valuable substrate for exploring new fluorination methodologies and studying structure-activity relationships (SAR) in academic and industrial R&D.

Basic Information

Product Name	4-(Trifluoromethyl)Cyclohexane-1-Carbaldehyde
CAS No.	1073722-40-3
Molecular Formula	C8H11F3O
Molecular Weight	180.17 g/mol
Synonyms	4-(Trifluoromethyl)cyclohexanecarboxaldehyde; 4-(Trifluoromethyl)cyclohexanecarbaldehyde; 4-Trifluoromethylcyclohexanecarbaldehyde; 4-Trifluoromethyl-1-cyclohexanecarboxaldehyde; 1-Formyl-4-(trifluoromethyl)cyclohexane; Cyclohexanecarboxaldehyde, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)cyclohexylcarbaldehyde
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Cyclohexane-1-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat sources and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.