Description

Piperidinomethyl-4-Phenylboronic Acid Pinacol Ester Hydrochloride is a high-value, protected boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating complex carbon-carbon bonds for small molecule APIs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Material Science: Enables the synthesis of organic electronic materials, such as those used in OLEDs and organic photovoltaics, via cross-coupling polymerization.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the creation of molecular probes for target identification and validation.
• Academic & Process Chemistry: A valuable reagent for methodological development, catalysis research, and scaling up synthetic routes in process chemistry.

Basic Information

Product Name	Piperidinomethyl-4-Phenylboronic Acid Pinacol Ester Hydrochloride
CAS No.	1073372-05-0
Molecular Formula	C18H29BClNO2
Molecular Weight	337.69 g/mol
Synonyms	4-(Piperidin-1-ylmethyl)phenylboronic acid pinacol ester hydrochloride; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]piperidine hydrochloride; 4-(Piperidinomethyl)phenylboronic acid pinacol ester HCl; (4-(Piperidin-1-ylmethyl)phenyl)boronic acid pinacol ester hydrochloride; B-(4-(Piperidinomethyl)phenyl)boronic acid pinacol ester hydrochloride; Piperidin-1-ylmethyl-phenyl-4-boronic acid pinacol ester hydrochloride; 1073372-05-0
EINECS	Contact for details

Quality Control

Our Piperidinomethyl-4-Phenylboronic Acid Pinacol Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.