Description

1-(Benzenesulfonyl)-1H-Pyrazole-4-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its role as a protected boronic acid, offering enhanced stability and solubility for use in cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable organoboron reagent for forming carbon-carbon bonds in the synthesis of biaryl and heterobiaryl compounds.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and functional polymers.
• Chemical Biology & Proteomics: Utilized as a molecular probe or linker in the development of chemical tools and bioconjugates.
• Academic & Industrial R&D: A versatile reagent for method development and exploratory synthesis in laboratory settings.

Basic Information

Product Name	1-(Benzenesulfonyl)-1H-Pyrazole-4-Boronic Acid Pinacol Ester
CAS No.	1073372-04-9
Molecular Formula	C15H19BN2O4S
Molecular Weight	334.20 g/mol
Synonyms	1-(Phenylsulfonyl)-1H-pyrazole-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(phenylsulfonyl)-1H-pyrazole; 1H-Pyrazole-4-boronic acid, 1-(benzenesulfonyl)-, 1,1-dimethylethyl ester; 1-Benzenesulfonyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-(Phenylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-(Benzenesulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole
EINECS	Contact for details

Quality Control

Our 1-(Benzenesulfonyl)-1H-Pyrazole-4-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.