Description

4-[3-Methyl-5-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridin-2-Yl]Morpholine is a high-value, synthetically versatile boronic ester derivative, crucial for modern organic synthesis. This compound serves as a key advanced pharmaceutical intermediate (API) and building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical building block for forming carbon-carbon bonds in the synthesis of complex organic molecules, particularly in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Serves as a precursor in the creation of novel herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Acts as a molecular probe or linker in the study of biological pathways and protein interactions.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening.

Basic Information

Item	Details
Product Name	4-[3-Methyl-5-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridin-2-Yl]Morpholine
CAS No.	1073372-03-8
Molecular Formula	C16H25BN2O3
Molecular Weight	304.20 g/mol
Synonyms	2-(4-Morpholinyl)-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-morpholinopyridine; 4-[3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]morpholine; 1073372-03-8; Boronic acid, B-[5-(4-morpholinyl)-3-methyl-2-pyridinyl]-, 1,1-dimethylethyl ester; 2-Morpholino-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 4-[3-Methyl-5-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridin-2-Yl]Morpholine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient humidity. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.