Description

2-(4-Acetylpiperazin-1-Yl)Pyridine-5-Boronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound matters as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecules for pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active compound libraries.
• Agrochemical Research: Used to construct complex heterocyclic scaffolds for developing new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Probe Development: Employed in the creation of bioconjugates and molecular probes for target identification and validation studies.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Academic & Contract Research: A valuable reagent for methodology development and exploring new catalytic systems in academic and CRO laboratory settings.

Basic Information

Product Name	2-(4-Acetylpiperazin-1-Yl)Pyridine-5-Boronic Acid, Pinacol Ester
CAS No.	1073372-01-6
Molecular Formula	C17H26BN3O3
Molecular Weight	331.22 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-[4-(acetyl)piperazin-1-yl]pyridine; 2-(4-Acetyl-1-piperazinyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(N-Acetylpiperazin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(4-Acetylpiperazin-1-yl)pyridine-5-boronic acid pinacol ester; 1073372-01-6; AKOS015903991; BRN 15305835
EINECS	Contact for details

Quality Control

Our 2-(4-Acetylpiperazin-1-Yl)Pyridine-5-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.