Description

2-Nitro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures with precision. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-couplings for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific pyridine-based structures.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CROs and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	2-Nitro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1073371-93-3
Molecular Formula	C11H15BN2O4
Molecular Weight	250.06 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-nitropyridine; 2-Nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Nitropyridine-5-boronic acid pinacol ester; 5-(2-Nitropyridin-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pyridine, 2-nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol 2-Nitropyridine-5-boronate; 5-(2-Nitro-5-pyridinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Nitro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.