Description

Morpholino(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methanone is a high-purity, advanced pharmaceutical intermediate featuring a pyridine core and a protected boronic ester functional group. This compound is a critical building block in modern medicinal chemistry, enabling efficient cross-coupling reactions for the synthesis of complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a key boronic ester reagent for constructing biaryl and heterobiaryl systems in drug discovery.
• Pharmaceutical Intermediate: For the synthesis of potential therapeutic agents targeting various diseases.
• Agrochemical Research: In the development of new crop protection agents and pesticides.
• Material Science: As a precursor for organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology: For the synthesis of probes and tool compounds used in biological target identification and validation.
• Process Chemistry: Scaling up synthetic routes for the commercial production of fine chemicals.

Basic Information

Product Name	Morpholino(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methanone
CAS No.	1073371-92-2
Molecular Formula	C16H23BN2O4
Molecular Weight	318.18 g/mol
Synonyms	(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)(morpholino)methanone; Morpholine, 4-[(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinyl)carbonyl]-; 3-(Morpholine-4-carbonyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinoyl morpholine; Boronic acid, B-[5-(4-morpholinylcarbonyl)-3-pyridinyl]-, 1,3-propanediol cyclic ester
EINECS	Contact for details

Quality Control

Our Morpholino(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). The product is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.