Description

4-[(N,n-Dimethylamino)Methyl]Benzeneboronic Acid Pinacol Ester Hydrochloride is a high-value, protected boronic acid derivative, essential as a key synthetic intermediate in modern organic and medicinal chemistry. Its primary value lies in its enhanced stability and solubility compared to the free boronic acid, facilitating crucial cross-coupling reactions like the Suzuki-Miyaura reaction. This compound is critically needed by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders, oncology, and inflammation.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, organoboron reagent for forming carbon-carbon bonds between aromatic rings, a cornerstone reaction in drug discovery and material science.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl scaffolds.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for catalysis or as a precursor for functionalized materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Advanced Material Precursor: Acts as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and OFETs.

Basic Information

Product Name	4-[(N,n-Dimethylamino)Methyl]Benzeneboronic Acid Pinacol Ester Hydrochloride
CAS No.	1073371-85-3
Molecular Formula	C16H27BClNO2
Molecular Weight	311.65 g/mol
Synonyms	4-(Dimethylaminomethyl)phenylboronic acid pinacol ester hydrochloride; [4-(Dimethylaminomethyl)phenyl]boronic acid pinacol ester hydrochloride; 4-(N,N-Dimethylaminomethyl)benzeneboronic acid pinacol ester HCl; (4-((Dimethylamino)methyl)phenyl)boronic acid pinacol ester hydrochloride; B-[4-(Dimethylaminomethyl)phenyl]-5,5-dimethyl-1,3,2-dioxaborinane hydrochloride; 1073371-85-3; Pinacol 4-(Dimethylaminomethyl)benzeneboronate hydrochloride
EINECS	Contact for details

Quality Control

Our 4-[(N,n-Dimethylamino)Methyl]Benzeneboronic Acid Pinacol Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research under stringent regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.