Description

2-Amino-5-Chlorophenylboronic Acid, Pinacol Ester is a high-value, protected boronic acid derivative crucial for modern synthetic chemistry. Its primary value lies in serving as a key synthetic intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its halogen and amino functionality.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs or sensors.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents due to the reactivity of the boronate ester group.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis studies.
• Ligand Synthesis: Used to prepare specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Amino-5-Chlorophenylboronic Acid, Pinacol Ester
CAS No.	1073371-77-3
Molecular Formula	C12H17BClNO2
Molecular Weight	253.53 g/mol
Synonyms	(2-Amino-5-chlorophenyl)boronic acid pinacol ester; 2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; 5-Chloro-2-aminophenylboronic acid pinacol ester; 2-Amino-5-chlorobenzeneboronic acid pinacol ester; Pinacol (2-amino-5-chlorophenyl)boronate; B-(2-Amino-5-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 1073371-77-3
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Chlorophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.