Description

4-(n-Boc-Phenylaminomethyl)Benzeneboronic Acid Pinacol Ester is a high-value, protected boronic acid ester building block designed for advanced organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to introduce functionalized aromatic segments into target molecules with precision.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, protected boronate reagent for palladium-catalyzed carbon-carbon bond formation under mild conditions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific aromatic architectures.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, liquid crystals, and light-emitting materials for electronic devices.
• Chemical Biology & Probe Development: Facilitates the creation of labeled compounds and molecular probes for biological target identification and study.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	4-(n-Boc-Phenylaminomethyl)Benzeneboronic Acid Pinacol Ester
CAS No.	1073371-71-7
Molecular Formula	C24H32BNO4
Molecular Weight	409.33 g/mol
Synonyms	4-[(N-Boc-anilino)methyl]benzeneboronic acid pinacol ester; 4-[(tert-Butoxycarbonyl)(phenyl)aminomethyl]phenylboronic acid pinacol ester; 4-[(N-Boc-phenylamino)methyl]phenylboronic acid pinacol ester; 4-(N-Boc-anilinomethyl)phenylboronic acid pinacol ester; [4-[[(1,1-Dimethylethoxy)carbonyl](phenyl)amino]methyl]phenyl]boronic acid pinacol ester; BOC-Protected Aminomethyl Phenylboronic Acid Pinacol Ester; (4-((N-Boc-phenylamino)methyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(n-Boc-Phenylaminomethyl)Benzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent hydrolysis of the boronate ester.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.